Shiga Toxin-Producing E. 杆菌(STEC)

App世界足球赛 supports research to understand how E. 杆菌 bacteria cause illness and identify the best possible treatments for people with E. 杆菌 感染.

Multiple teams of scientists are looking into how E. 杆菌 causes disease, including enterohemmaorrhagic Shiga toxin-producing E. 杆菌 (known to scientists as EHEC/STEC). EHEC/STEC causes severe disease and sometimes death. App世界足球赛ers are uncovering the basic mechanisms of how the bacteria damages human cells and systems and identifying factors associated with the severest forms of the disease.


By studying the human genome, researchers have identified special, small molecules that stop bacteria from producing toxins and other molecules that can cause a severe bacterial infection and illness or death.

App世界足球赛-funded research has uncovered complex communication systems in bacteria that allow pathogens such as E. 杆菌 0157:H7 to hide until the bacteria launch coordinated attacks with overwhelming numbers of bacteria.

Other researchers have discovered that antibiotic therapy does not help people with bloody diarrhea and can even cause more harm during some types of severe 感染.

App世界足球赛ers are designing and testing monoclonal antibodies and other therapies to treat STEC infection before it progresses into severe, life-threatening forms.

App世界足球赛 also provides funding to develop models for testing potential medicines before they are used in human clinical trials.

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